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Restek Raptor™ Polar X 90 Å HPLC Columns
Innovative Hybrid Selectivity for Highly Polar Compounds
The Restek Raptor™ Polar X 90 Å HPLC column series has been engineered to overcome one of the greatest challenges in liquid chromatography: the efficient retention and separation of highly polar analytes. Its proprietary stationary phase combines hydrophilic interaction chromatography (HILIC) with weak anion-exchange (WAX) functionality, providing a versatile platform that enables analysts to tailor retention mechanisms through simple mobile phase adjustments.
Unlike conventional HILIC columns that rely solely on hydrophilic partitioning, the Raptor Polar X stationary phase allows seamless transitions between HILIC and ion-exchange retention. This unique hybrid chemistry significantly expands method development possibilities while minimizing equilibration times compared with many traditional HILIC stationary phases.
Built on Restek's proven 2.7 µm superficially porous (core-shell) silica technology with a 90 Å pore size, the Raptor Polar X delivers outstanding efficiency, sharp peak shapes, and excellent reproducibility on both HPLC and UHPLC systems..
Key Benefits
- Proprietary hybrid stationary phase combining HILIC and weak anion-exchange (WAX) retention mechanisms.
- Rapid switching between HILIC and ion-exchange modes through simple mobile phase modifications.
- Excellent retention of highly polar compounds that exhibit little or no retention on conventional reversed-phase columns.
- Outstanding selectivity for acidic, basic, zwitterionic, and permanently charged analytes.
- Reduced equilibration times compared with many traditional HILIC columns.
- Excellent peak symmetry and chromatographic efficiency.
- Core-shell particle technology provides UHPLC performance with moderate backpressure.
- Fully compatible with LC-MS/MS using volatile mobile phases.
- Robust performance suitable for routine analytical laboratories and demanding research applications.
Find more information in the Restek Raptor Polar X Brochure.
| Product Number | Description | Price | Specifications |
|---|
| RT-9311A0252 | Raptor Polar X 90Å 2.7µm, 2.1 x 5mm Guard Cartridge (EXP), pk.3 |
EUR 715.00
Will be procured as soon as possible |
- Product Number: RT-9311A0252
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 5 mm
- Column ID: 2.1 mm
- Hardware Material: Stainless Steel
- Hardware Type: Guard Cartridge
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Accessories: Guard Cartridge
- Package Size: 3
Questions about the article
To the product details
Will be procured as soon as possible
| RT-9311A0253 | Raptor Polar X 90Å 2.7µm, 3.0 x 5mm Guard Cartridge (EXP), pk.3 | Price on request |
- Product Number: RT-9311A0253
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 5 mm
- Column ID: 3.0 mm
- Hardware Material: Stainless Steel
- Hardware Type: Guard Cartridge
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Accessories: Guard Cartridge
- Package Size: 3
| RT-9311A12 | Raptor Polar X 90Å 2.7µm, 2.1 x 100mm, ea. |
EUR 1,100.00
Will be procured as soon as possible |
- Product Number: RT-9311A12
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 100 mm
- Column ID: 2.1 mm
- Hardware Material: Stainless Steel
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
| RT-9311A32 | Raptor Polar X 90Å 2.7µm, 2.1 x 30mm, ea. |
EUR 978.00
Will be procured as soon as possible |
- Product Number: RT-9311A32
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 30 mm
- Column ID: 2.1 mm
- Hardware Material: Stainless Steel
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
| RT-9311A52 | Raptor Polar X 90Å 2.7µm, 2.1 x 50mm, ea. |
EUR 1,039.00
Will be procured as soon as possible |
- Product Number: RT-9311A52
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 50 mm
- Column ID: 2.1 mm
- Hardware Material: Stainless Steel
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
| RT-9311A12-T | Raptor Inert Polar X 90Å 2.7µm, 2.1 x 100mm (Surface Passivated Hardware), ea. |
EUR 1,289.00
Will be procured as soon as possible |
- Product Number: RT-9311A12-T
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 100 mm
- Column ID: 2.1 mm
- Hardware Material: SS Surface passivated
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
| RT-9311A32-T | Raptor Inert Polar X 90Å 2.7µm, 2.1 x 30mm (Surface Passivated Hardware), ea. |
EUR 1,139.00
Will be procured as soon as possible |
- Product Number: RT-9311A32-T
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 30 mm
- Column ID: 2.1 mm
- Hardware Material: SS Surface passivated
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
| RT-9311A52-T | Raptor Inert Polar X 90Å 2.7µm, 2.1 x 50mm (Surface Passivated Hardware), ea. |
EUR 1,199.00
Will be procured as soon as possible |
- Product Number: RT-9311A52-T
- Manufacturer: Restek
- Brand: Raptor
- Selectivity: Mixed-Mode
- Selectivity Manufacturer: Polar X
- Particle Size: 2.7 µm
- Pore Volume: 0.30 mL/g
- Pore Size: 90 Å
- Column Length: 50 mm
- Column ID: 2.1 mm
- Hardware Material: SS Surface passivated
- Hardware Type: Analytical Column
- Application: Mixed-Mode
- Temperature Range: 60 °C
- pH Range: 2-8
- Particle: Silica
- Particle Shape: Spherical
- Particle Type: Core-Shell
- Surface Area: 130 m2/g
- Package Size: 1
Will be procured as soon as possible
Typical Applications
The Raptor Polar X stationary phase is ideally suited for compounds that are difficult to retain using conventional reversed-phase chromatography and for applications requiring orthogonal selectivity.
Typical applications include:
- Highly polar pesticides (QuPPe methods)
- Glyphosate, glufosinate and AMPA
- Chlorate and perchlorate
- Organic acids
- Inorganic anions
- Amino acids
- Biogenic amines
- Small polar metabolites
- Pharmaceutical impurities
- Drug metabolites
- Clinical biomarkers
- Environmental contaminants
- Food safety testing
- Forensic toxicology
The unique combination of HILIC and ion-exchange interactions frequently improves analyte retention, reduces matrix effects, and enhances LC-MS/MS sensitivity, making the column particularly valuable for trace-level quantitative analyses.
Technical Specifications
| Specification | Description |
|---|---|
| Stationary Phase | Proprietary Polar X hybrid phase |
| Separation Mechanisms | Hydrophilic Interaction (HILIC) and Weak Anion Exchange (WAX) |
| Particle Technology | Superficially Porous (Core-Shell) Silica |
| Particle Size | 2.7 µm |
| Pore Size | 90 Å |
| USP Classification | L68 |
| Surface Chemistry | Hybrid polar stationary phase with ion-exchange functionality |
| Recommended pH Range | 2.0–8.0 |
| Maximum Operating Pressure | Compatible with UHPLC and HPLC systems (instrument dependent) |
| Mobile Phase Compatibility | Acetonitrile, methanol, aqueous buffers, ammonium formate, ammonium acetate, formic acid, LC-MS compatible solvents |
| LC-MS Compatibility | Excellent with volatile mobile phases |
| Available Column Dimensions | Multiple analytical and UHPLC formats available |
Why Choose Raptor™ Polar X?
The Raptor Polar X 90 Å provides laboratories with a unique chromatographic solution for challenging polar analytes that are poorly retained on conventional reversed-phase columns. Its innovative hybrid stationary phase simplifies method development by allowing analysts to optimize selectivity through straightforward mobile phase adjustments rather than changing column chemistry.
Combined with Restek's advanced core-shell particle technology, the Raptor Polar X offers exceptional efficiency, reproducibility, and robustness while maintaining compatibility with both HPLC and UHPLC instrumentation. This versatility makes it an ideal choice for pharmaceutical, environmental, food safety, clinical, and forensic laboratories requiring reliable analysis of highly polar compounds.
Available Column Dimensions
The Raptor Polar X 90 Å series is available in several column formats to support routine analysis, method development, and high-throughput LC-MS/MS workflows.
- Lengths: 30, 50, 100 and 150 mm
- Internal Diameters: 2.1, 3.0 and 4.6 mm
- Particle Size: 2.7 µm
- Pore Size: 90 Å
The wide range of column dimensions allows straightforward scaling between UHPLC and conventional HPLC methods while maintaining excellent chromatographic performance and method robustness.