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Key Advantages

Excellent Method Scalability

  • Direct transfer between HPLC and UHPLC systems.
  • Available in 1.8 µm, 3 µm, and 5 µm particle sizes.
  • Simplifies method development and validation.

Outstanding Reproducibility

  • Consistent batch-to-batch performance.
  • Reliable retention times and selectivity.
  • Suitable for regulated pharmaceutical and bioanalytical laboratories.

Long Column Lifetime

  • Designed to withstand demanding UHPLC operating conditions.
  • High mechanical stability and durability.
  • Excellent value for routine and high-throughput laboratories.

LC-MS Compatibility

  • Selective stationary phases enable the use of simple, MS-friendly mobile phases.
  • Improved sensitivity and reduced ion suppression in many LC-MS applications.

Selectivity Options

Force C18

  • General-purpose end-capped octadecylsilane reversed-phase column.
  • Highest hydrophobic retention within the Force family.
  • Broad applicability and ideal for pharmaceutical, environmental, food safety, clinical and bioanalytical applications.
  • USP L1

Force Biphenyl

  • Enhanced retention and resolution for dipolar, conjugated, and aromatic compounds.
  • Particularly effective for forensic toxicology and pharmaceutical analyses.
  • USP L11

Force FluoroPhenyl

  • Offers orthogonal selectivity compared to C18 and combines multiple interaction mechanisms for challenging separations.
  • Supports both reversed-phase and HILIC separations.
  • Improved separation of positional isomers and halogenated compounds.
  • USP L43

Conclusion

The Restek Force LC Column Series delivers dependable chromatographic performance through a combination of proven stationary phases, robust fully porous particle technology, and complete HPLC/UHPLC scalability. Whether laboratories require a versatile C18, the unique selectivity of Biphenyl, or the dual-mode capabilities of FluoroPhenyl, Force columns provide reproducible separations, long service life, and outstanding analytical flexibility across pharmaceutical, environmental, food, forensic, and bioanalytical applications.

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