Agilent PLRP-S polymeric reversed-phase HPLC Columns

PLRP-S Series

Agilent PLRP-S Polymer HPLC Columns

Agilent PLRP-S HPLC columns use a highly cross-linked, rigid polystyrene-divinylbenzene (PS-DVB) copolymer as the reversed-phase stationary phase. Unlike silica-based reversed-phase materials, the PLRP-S particle is inherently hydrophobic and does not require bonded groups. The polymeric structure provides broad chemical and thermal stability for demanding reversed-phase LC applications.

The spherical, macroporous PS-DVB particles maintain their structure when changing between aqueous and organic mobile phases without swelling or shrinking. Because the stationary phase contains no silica, it is also free from residual silanol groups that can cause secondary interactions with basic compounds and amines.

PLRP-S media are available in different particle sizes (3 µm, 5 µm, 8 µm, 10 µm, 15–20 µm and 30–50 µm) and different pore sizes (100 Å, 300 Å, 1000 Å and 4000 Å) for analytical and preparative chromatography. The consistent polymer chemistry allows methods to be transferred from analytical screening to larger-scale purification while maintaining the same fundamental stationary-phase selectivity.

PLRP-S Overview

Highly cross-linked PS-DVB polymeric stationary phase
Stable across a pH range of 1.0–14.0
Suitable for clean-in-place (CIP) procedures using aggressive alkaline solutions such as 1M NaOH
Maximum operating temperature up to 200 °C
Pore size of 100 Å designed for small molecules below approximately 2,000 Da
Pore size of 300 Å designed for biomolecules up to approximately 100,000 Da
Pore sizes of 1000 Å and 4000 Å designed for large macromolecular structures like large globular proteins to monoclonal antibodies (mAbs) and DNA fragments

Use the product filters below to select the appropriate Agilent PLRP-S HPLC column according to pore size, particle size, molecular-weight range, column dimensions and reversed-phase application.

168 Products

Product Number	Description	Price	Specifications

AT-PL1111-3500

PLRP-S 100Å 5µm, 4.6 x 150mm, ea.

EUR 829.00

Will be procured as soon as possible

Product Number: AT-PL1111-3500
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 5.0 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 4.6 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 829.00

Will be procured as soon as possible

AT-PL1112-1801

PLRP-S 300Å 8µm, 7.5 x 50mm, ea.

EUR 1,038.00

Will be procured as soon as possible

Product Number: AT-PL1112-1801
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,038.00

Will be procured as soon as possible

AT-PL1112-1802

PLRP-S 1000Å 8µm, 7.5 x 50mm, ea.

EUR 1,024.00

Will be procured as soon as possible

Product Number: AT-PL1112-1802
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,024.00

Will be procured as soon as possible

AT-PL1112-1803

PLRP-S 4000Å 8µm, 7.5 x 50mm, ea.

EUR 1,024.00

Will be procured as soon as possible

Product Number: AT-PL1112-1803
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 4‘000 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 139 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,024.00

Will be procured as soon as possible

AT-PL1112-1803CU

PLRP-S 4000Å 8µm, 7.5 x 50mm (for Curevac), ea.

EUR 897.00

Will be procured as soon as possible

Product Number: AT-PL1112-1803CU
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 4‘000 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 139 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 897.00

Will be procured as soon as possible

AT-PL1112-3801

PLRP-S 300Å 8µm, 7.5 x 150mm, ea.

EUR 1,197.00

Will be procured as soon as possible

Product Number: AT-PL1112-3801
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,197.00

Will be procured as soon as possible

AT-PL1112-3802

PLRP-S 1000Å 8µm, 7.5 x 150mm, ea.

EUR 1,355.00

Will be procured as soon as possible

Product Number: AT-PL1112-3802
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,355.00

Will be procured as soon as possible

AT-PL1112-6800

PLRP-S 100Å 8µm, 7.5 x 300mm, ea.

EUR 1,685.00

Will be procured as soon as possible

Product Number: AT-PL1112-6800
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 300 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,685.00

Will be procured as soon as possible

AT-PL1112-6801

PLRP-S 300Å 8µm, 7.5 x 300mm, ea.

EUR 1,870.00

Will be procured as soon as possible

Product Number: AT-PL1112-6801
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 300 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

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Price:

EUR 1,870.00

Will be procured as soon as possible

AT-PL1112-6802

PLRP-S 1000Å 8µm, 7.5 x 300mm, ea.

EUR 1,941.00

Will be procured as soon as possible

Product Number: AT-PL1112-6802
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 300 mm
Column ID: 7.5 mm
Hardware Material: Stainless Steel
Hardware Type: Analytical Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 1,941.00

Will be procured as soon as possible

AT-PL1212-1102

PLRP-S 1000Å 10µm, 25.0 x 50mm, ea.

EUR 2,985.00

Will be procured as soon as possible

Product Number: AT-PL1212-1102
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 2,985.00

Will be procured as soon as possible

AT-PL1212-1103

PLRP-S 4000Å 10µm, 25.0 x 50mm, ea.

EUR 2,985.00

Will be procured as soon as possible

Product Number: AT-PL1212-1103
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 4‘000 Å
Endcapping: n.a.
Column Length: 50 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 139 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 2,985.00

Will be procured as soon as possible

AT-PL1212-3100

PLRP-S 100Å 10µm, 25.0 x 150mm, ea.

EUR 3,160.00

Will be procured as soon as possible

Product Number: AT-PL1212-3100
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,160.00

Will be procured as soon as possible

AT-PL1212-3101

PLRP-S 300Å 10µm, 25.0 x 150mm, ea.

EUR 3,812.00

Will be procured as soon as possible

Product Number: AT-PL1212-3101
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,812.00

Will be procured as soon as possible

AT-PL1212-3102

PLRP-S 1000Å 10µm, 25.0 x 150mm, ea.

EUR 3,812.00

Will be procured as soon as possible

Product Number: AT-PL1212-3102
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,812.00

Will be procured as soon as possible

AT-PL1212-3103

PLRP-S 4000Å 10µm, 25.0 x 150mm, ea.

EUR 3,812.00

Will be procured as soon as possible

Product Number: AT-PL1212-3103
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 4‘000 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 139 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,812.00

Will be procured as soon as possible

AT-PL1212-3201

PLRP-S 300Å 15-20µm, 25.0 x 150mm, ea.

EUR 3,233.00

Will be procured as soon as possible

Product Number: AT-PL1212-3201
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 15-20 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,233.00

Will be procured as soon as possible

AT-PL1212-3702

PLRP-S 1000Å 30µm, 25.0 x 150mm, ea.

EUR 3,367.00

Will be procured as soon as possible

Product Number: AT-PL1212-3702
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 30 µm
Pore Size: 1‘000 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 267 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,367.00

Will be procured as soon as possible

AT-PL1212-3703

PLRP-S 4000Å 30µm, 25.0 x 150mm, ea.

EUR 3,367.00

Will be procured as soon as possible

Product Number: AT-PL1212-3703
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 30 µm
Pore Size: 4‘000 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 139 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,367.00

Will be procured as soon as possible

AT-PL1212-3800

PLRP-S 100Å 8µm, 25.0 x 150mm, ea.

EUR 3,334.00

Will be procured as soon as possible

Product Number: AT-PL1212-3800
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,334.00

Will be procured as soon as possible

AT-PL1212-3801

PLRP-S 300Å 8µm, 25.0 x 150mm, ea.

EUR 3,764.00

Will be procured as soon as possible

Product Number: AT-PL1212-3801
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 150 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 3,764.00

Will be procured as soon as possible

AT-PL1212-4100

PLRP-S 100Å 10µm, 25.0 x 25mm Guard Column (1/8"), ea.

EUR 1,581.00

Will be procured as soon as possible

Product Number: AT-PL1212-4100
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 25 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Prep Guard Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 1,581.00

Will be procured as soon as possible

AT-PL1212-4201

PLRP-S 300Å 20µm, 25.0 x 25mm Guard Column, ea.

EUR 1,581.00

Will be procured as soon as possible

Product Number: AT-PL1212-4201
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 20 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 25 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Prep Guard Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 1,581.00

Will be procured as soon as possible

AT-PL1212-4800

PLRP-S 300Å 8µm, 25.0 x 25mm Guard Column (1/16"), ea.

EUR 1,581.00

Will be procured as soon as possible

Product Number: AT-PL1212-4800
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 8.0 µm
Pore Size: 300 Å
Endcapping: n.a.
Column Length: 25 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Prep Guard Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 384 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 1,581.00

Will be procured as soon as possible

AT-PL1212-6100

PLRP-S 100Å 10µm, 25.0 x 300mm, ea.

EUR 4,436.00

Will be procured as soon as possible

Product Number: AT-PL1212-6100
Manufacturer: Agilent
Brand: PLRP-S
Selectivity: PSDVB
Selectivity Manufacturer: PLRP-S
Particle Size: 10 µm
Pore Size: 100 Å
Endcapping: n.a.
Column Length: 300 mm
Column ID: 25.0 mm
Hardware Material: Stainless Steel
Hardware Type: Preparative Column
Application: Reversed Phase
USP Code: L21
Temperature Range: 200 °C
pH Range: 1-14
Particle: Polymer
Particle Shape: Spherical
Particle Type: Fully Porous
Surface Area: 550 m2/g
Bonding Type: n.a.
Package Size: 1

Questions about the article To the product details

Price:

EUR 4,436.00

Will be procured as soon as possible

Agilent PLRP-S Polymer HPLC Columns

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