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Ideal Applications

The Raptor ARC-18 stationary phase is an excellent general-purpose reversed-phase column for laboratories requiring robust and reproducible separations across a diverse range of analytes.

Typical applications include:

  • Pharmaceutical active ingredients (APIs)
  • Pharmaceutical impurities and degradation products
  • Stability-indicating methods
  • Quality control testing
  • Drug metabolites
  • Veterinary drug residues
  • Food contaminants
  • Mycotoxins
  • Pesticides and herbicides
  • Environmental pollutants
  • Clinical and bioanalytical samples
  • Forensic toxicology
  • Natural products
  • Industrial chemical analysis

Its balanced C18 selectivity makes the Raptor ARC-18 particularly effective for multi-residue methods, where reliable retention and reproducibility are essential across compounds with varying chemical properties.

Technical Specifications

Specification Description
Stationary Phase Proprietary ARC-18 bonded phase
Particle Technology Superficially Porous (Core-Shell) Silica
Particle Size 2.7 µm
Pore Size 90 Å
USP Classification L1
Carbon Load Optimized for balanced reversed-phase retention and reproducibility
Separation Mechanism Hydrophobic (reversed-phase) interactions
Surface Chemistry High-purity, fully endcapped C18 bonded silica
Recommended pH Range 2.0–8.0
Maximum Operating Pressure Compatible with HPLC and UHPLC systems (instrument dependent)
Mobile Phase Compatibility Water, methanol, acetonitrile, phosphate buffers, ammonium formate, ammonium acetate, formic acid, and other LC-MS compatible mobile phases
LC-MS Compatibility Excellent with volatile mobile phases
Available Column Dimensions Multiple analytical and UHPLC formats available

Why Choose the Raptor™ ARC-18 90 Å?

The Restek Raptor ARC-18 90 Å offers a highly reliable reversed-phase solution for laboratories seeking consistent chromatographic performance across a broad range of applications. Its optimized ARC-18 chemistry provides excellent reproducibility while maintaining balanced retention for compounds with diverse physicochemical properties.

Combined with Restek's advanced core-shell particle technology, the Raptor ARC-18 delivers shorter run times, higher efficiency, and excellent peak shapes without requiring UHPLC-exclusive instrumentation. The result is simplified method development, reliable method transfer, and robust routine performance.

Whether used in pharmaceutical development, food safety laboratories, environmental testing, clinical research, or quality control, the Raptor ARC-18 90 Å provides the versatility and reliability demanded by modern analytical laboratories.

Available Column Dimensions

The Restek Raptor ARC-18 90 Å HPLC series is available in multiple configurations to accommodate a wide range of analytical workflows.

  • Particle Size: 2.7 µm
  • Pore Size: 90 Å
  • Internal Diameters: 2.1 mm, 3.0 mm, and 4.6 mm
  • Column Lengths: 30 mm, 50 mm, 100 mm, and 150 mm

These dimensions allow straightforward scaling between conventional HPLC and UHPLC methods while maintaining chromatographic performance, sensitivity, and robustness.

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