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Stationary Phase Categories of Restek Raptor LC Columns

  • Raptor C18
    • General-purpose reversed-phase column.
    • Highest hydrophobic retention within the Raptor family.
    • Ideal for pharmaceutical, environmental, food safety, and bioanalytical applications.
  • Raptor C8
    • Similar selectivity to C18 with reduced retention for nonpolar compounds.
    • Faster analysis times for many applications.
    • Excellent choice for food, clinical, environmental, and cannabis testing laboratories.
  • Raptor Biphenyl
    • Enhanced retention for aromatic, conjugated, and polar compounds.
    • Particularly effective for forensic toxicology and pharmaceutical analyses.
  • Raptor FluoroPhenyl
    • Alternative selectivity for structurally related analytes.
    • Improved separation of positional isomers and halogenated compounds.
  • Raptor ARC-18
    • Sterically protected C18 phase.
    • Optimized for low-pH LC-MS applications.
    • Enhanced stability under acidic mobile phase conditions.
  • Raptor HILIC-Si
    • Bare silica stationary phase.
    • Suitable for highly polar compounds and HILIC separations.
  • Raptor Polar X
    • Unique hybrid phase.
    • Suitable for highly polar compounds through a balance of two retention mechanisms.

Key Advantages of Restek Raptor LC Columns

  • Fast Analysis Times
    • Core-shell particle technology enables rapid separations while maintaining excellent resolution.
    • Reduced diffusion pathways improve mass transfer and chromatographic efficiency.
  • High Efficiency and Resolution
    • Superior peak capacity compared to conventional fully porous particle columns.
    • Sharp, symmetrical peak shapes improve quantitation accuracy and sensitivity.
  • Low Backpressure
    • Achieve UHPLC-like performance on many conventional HPLC systems.
    • Increased throughput without requiring extensive instrument upgrades.
  • Excellent Reproducibility
    • Consistent batch-to-batch performance ensures reliable analytical results.
    • Ideal for regulated laboratories and validated methods.
  • Exceptional Ruggedness
    • Designed for long column lifetime and demanding routine analyses.
    • Suitable for high-throughput laboratories and complex sample matrices.

Conclusion

The Restek Raptor LC Column Series delivers an exceptional combination of speed, efficiency, selectivity, and durability. By integrating advanced core-shell particle technology with highly selective stationary phases, Raptor columns enable laboratories to achieve superior chromatographic performance, faster method development, and higher sample throughput while maintaining excellent reproducibility and ruggedness across a wide range of analytical applications.

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