LCTech CrossTOX – SPE Sample Clean-Up for Multi-Mycotoxin LC-MS/MS Analysis

LCTech CrossTOX is an advanced solid-phase extraction (SPE) clean-up solution designed for the simultaneous determination of multiple mycotoxins in food and feed samples. The non-retentive, non-dispersive SPE technology selectively reduces matrix interferences while allowing target mycotoxins to pass through the column for subsequent LC-MS/MS analysis.

The CrossTOX clean-up columns enable rapid sample preparation using a simple push-through or pull-through procedure without additional washing steps. This approach reduces solvent consumption, minimizes sample handling and supports reproducible multi-mycotoxin analysis. CrossTOX can be processed manually or automated using the LCTech FREESTYLE system, supporting unattended sample preparation and optional direct HPLC injection.

CrossTOX supports multi-mycotoxin analysis covering aflatoxins B1, B2, G1 and G2, sterigmatocystin, ochratoxin A, fumonisins B1 and B2, deoxynivalenol (DON), nivalenol, 15-acetyl-DON, 3-acetyl-DON, DON-3-glucoside, zearalenone, T-2 toxin, HT-2 toxin, citrinin and diacetoxyscirpenol. The clean-up procedure is designed to reduce interfering matrix components while maintaining suitable analyte recovery for subsequent LC-MS/MS determination.

LCTech CrossTOX SPE columns are suitable for food safety testing, animal feed analysis, cereal and grain monitoring, nut analysis and routine multi-mycotoxin screening. The combination of efficient matrix reduction, simplified sample preparation and LC-MS/MS compatibility supports reliable analytical workflows for laboratories monitoring mycotoxin contamination.

Use the product filters below to select the appropriate LCTech CrossTOX SPE columns and accessories for manual or automated multi-mycotoxin sample preparation.