Restek Raptor™ Polar X 90 Å HPLC Columns

Innovative Hybrid Selectivity for Highly Polar Compounds

The Restek Raptor™ Polar X 90 Å HPLC column series has been engineered to overcome one of the greatest challenges in liquid chromatography: the efficient retention and separation of highly polar analytes. Its proprietary stationary phase combines hydrophilic interaction chromatography (HILIC) with weak anion-exchange (WAX) functionality, providing a versatile platform that enables analysts to tailor retention mechanisms through simple mobile phase adjustments.

Unlike conventional HILIC columns that rely solely on hydrophilic partitioning, the Raptor Polar X stationary phase allows seamless transitions between HILIC and ion-exchange retention. This unique hybrid chemistry significantly expands method development possibilities while minimizing equilibration times compared with many traditional HILIC stationary phases.

Built on Restek's proven 2.7 µm superficially porous (core-shell) silica technology with a 90 Å pore size, the Raptor Polar X delivers outstanding efficiency, sharp peak shapes, and excellent reproducibility on both HPLC and UHPLC systems..

Key Benefits

• Proprietary hybrid stationary phase combining HILIC and weak anion-exchange (WAX) retention mechanisms.
• Rapid switching between HILIC and ion-exchange modes through simple mobile phase modifications.
• Excellent retention of highly polar compounds that exhibit little or no retention on conventional reversed-phase columns.
• Outstanding selectivity for acidic, basic, zwitterionic, and permanently charged analytes.
• Reduced equilibration times compared with many traditional HILIC columns.
• Excellent peak symmetry and chromatographic efficiency.
• Core-shell particle technology provides UHPLC performance with moderate backpressure.
• Fully compatible with LC-MS/MS using volatile mobile phases.
• Robust performance suitable for routine analytical laboratories and demanding research applications.

Find more information in the Restek Raptor Polar X Brochure.